A catheter-based treatment reduced early clinical deterioration in patients with intermediate-high risk acute pulmonary embolism compared with anticoagulation alone, according to findings from the PRAGUE-26 trial.
Optical coherence tomography (OCT) was noninferior to intravascular ultrasound (IVUS) for guiding percutaneous coronary intervention (PCI) in patients with true distal left main bifurcation lesions, according to late-breaking data from the ISOLEDS trial.
A selective approach based on “gatekeeper” stress testing to find older non-ST segment elevation (NSTEMI) patients most likely to benefit from invasive management fails to prove noninferior to routine angiography for 1-year major adverse cardiac and cerebrovascular events (MACCE), investigators in the EVAOLD study say.
A 1-year tailored exercise program cut atrial fibrillation (AF) burden by 45% compared with usual care in patients with non-permanent AF, according to results from the Norwegian Exercise in Atrial Fibrillation (NEXAF) trial presented at the European Society of Cardiology (ESC) Congress 2026 in Munich, Germany.
Hypoattenuated leaflet thickening (HALT) is reduced in patients undergoing transcatheter aortic valve replacement (TAVR) when patients take blood thinners, even when they don’t demonstrate a need for oral anticoagulants, results from the NOTION-4 study show.
Anticoagulation monotherapy after transcatheter aortic valve implant (TAVI) nearly halves the risk of subclinical valve leaflet thrombosis while remaining noninferior for safety, according to new trial findings.
Left atrial appendage (LAA) closure during open-heart surgery is only beneficial for high-risk patients, the European LAACS-2 trial shows, but this benefit is not restricted solely to AF.
Adding transcatheter tricuspid valve repair to medical therapy reduces all-cause mortality and heart failure hospitalization, and improves quality of life, in high-risk patients with severe tricuspid regurgitation (TR), according to late-breaking data from the TRIC-I-HF trial.
A strategy of transcatheter aortic valve (TAVI) implantation before percutaneous coronary intervention (PCI) is noninferior at 1-year for adverse events versus PCI before TAVI in patients with severe aortic stenosis (AS) and concomitant coronary artery disease (CAD), according to TAVI PCI study results.
Functional coronary angiography is better than conventional angiography for lowering rates of cardiovascular events after complete revascularization in patients with severe heart attacks and multivessel disease (MVD), results from the AIR-STEMI trial show.
Nathan Gray, CRTonline.org
Will Chu, CRTonline.org
Natalie Morrison, CRTonline.org
Bailey G. Salimes, CRTonline.org
Michael Mahmoudi, MD - S Khan, et al; JACC 2026; 88:4-18
Michael Mahmoudi, MD - Y Sotomi, et al; Lancet 2026; 408:440-452
Michael Mahmoudi, MD - J Tian, et al; NEJM 2026; 395:233-2342
In patients with severe TR who are suitable for repair or replacement, what would be your first choice?
Edge to Edge Repair
Valve Replacement
Georges Ephrem, Abdul Moiz Hafiz, John T. Saxon, Eric Horlick, Srinivasa Potluri, Allison Tsao, Harsimran Singh, Joanna Ghobrial, C. Huie Lin, John D. Serfas, Shamane Kimara March
Sania Zahrani, Rifqi Rizkani Eri, Muhammad Maulana Wildani, Suci Indriani, Ruth Grace Aurora, Taofan Taofan, Suko Adiarto, Iwan Dakota
Dharmindra Dulal, Ahmed Maraey, Vahid Yazdi, Juan Carlo Avalon, Cezar Iliescu, Mehmet Cilingiroglu, Konstantinos Marmagkiolis, Konstantinos Dean Boudoulas
Sunny Goel; Andy Moyal
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