Patients undergoing transcatheter aortic valve replacement (TAVR)-in-TAVR have a variety of prosthesis options with safe outcomes, but more research is required to determine the best-fit device for individual patients, a study from the PANDORA registry shows. 

Women experience a high lifetime risk of cardiovascular disease despite often developing events later than men, according to a review of nearly eight decades of Framingham Heart Study findings.  

The more severe the stroke, the greater the risk of dementia and faster cognitive and executive functioning decline, health experts say. 

Patients with severe asymptomatic aortic stenosis (AS) and myocardial fibrosis do not have improved clinical outcomes after early aortic valve intervention, results from the EVOLVED randomized clinical trial show. 

Obesity in heart failure with reduced ejection fraction (HFrEF) should be conceptualized as a modifiable disease amplifier that influences progression and clinical trajectory rather than a primary etiologic driver, according to researchers in a state-of-the-art review. 

Artificial Intelligence (AI) analysis of routine cardiac CT scans could help identify patients at increased risk of future heart failure before symptoms develop, according to new research. 

Single chronic total occlusion (CTO) patients treated with percutaneous coronary intervention (PCI) fared better in quality of life (QoL) and angina endpoints than those on optimal medical therapy (OMT), a new post-hoc analysis found.  

Not even one-quarter of veterans with heart failure with reduced ejection fraction (HFrEF) receive timely quadruple guideline-directed medical therapy (GDMT) after diagnosis of heart failure, a new study shows. 

Men have a better chance of long-term survival compared with women after left internal mammary artery (LIMA) grafting plus multiarterial grafting (MAG) during coronary artery bypass grafting (CABG) in patients with kidney failure, a new study shows.