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Experts Warn Over Lack of Evidence for IVUS in Peripheral Interventions

Aug 01, 2022 by
Nathan Gray, CRTonline.org

While the use of intravascular ultrasound (IVUS) imaging has been shown to reduce adverse event risk in percutaneous coronary intervention (PCI), the evidence for its use for peripheral interventions is still uncertain, warn experts.

Deep Learning Algorithms Applied to ECG Could Form New Type of Valvular Heart Disease Screening

Aug 01, 2022 by
Natalie Morrison, CRTonline.org

Machine learning analysis of 12-lead electrocardiography (ECG) could provide a new type of valvular heart disease (VHD) screening program, said researchers on a new study that found “deep learning” algorithms could accurately detect aortic stenosis (AS), aortic regurgitation (AR) and mitral regurgitation (MR).

US Cardiovascular Disease Risk and Prevalence Rates to Soar from 2025 to 2060: Population Study

Aug 01, 2022 by
Natalie Morrison, CRTonline.org

Cardiovascular disease prevalence will soar between 2025 and 2060 in the U.S., according to a new population study, which also predicts that racial and ethnic minorities will be disproportionately affected.

Nurse-Performed Lung and IVC Ultrasound May Provide Crucial Pre-Discharge Diagnostics

Jul 25, 2022 by
Nathan Gray, CRTonline.org

Pre-discharge lung and inferior vena cava (IVC) assessment (LUICA) performed by heart failure (HF) nurses can provide crucial diagnostic support that is predictive of acute decompensated heart failure (ADHF) outcomes, a new trial suggests.

FDA-Accepted Levels of Watchman Peridevice Leak Linked With Greater Long-Term Thromboembolism Risk

Jul 25, 2022 by
Natalie Morrison, CRTonline.org

A post-implantation peridevice leak (PDL) of 5 mm or less after percutaneous left atrial appendage (LAA) closure with the Watchman device is linked with greater risk of thromboembolism over 5 years, a new follow-up study has found.

Animal Data Suggest Serotonin Receptor Antagonist Cyproheptadine May Block Post-MI Valve Remodeling

Jul 25, 2022 by
Nathan Gray, CRTonline.org

The 5-hydroxytryptamine (5-HT: or serotonin) type 2B receptor (5-HT2BR) antagonist cyproheptadine reduces 5-HT levels after myocardial infarction (MI), prevents valvular fibrotic remodeling, and is associated with a larger increase in mitral valve size and less mitral regurgitation (MR), new lab and animal data suggest.

Genetic Predictors of Aortic Stenosis and Aortic Aneurysm Defined in New UK Biobank Analysis

Jul 25, 2022 by
Natalie Morrison, CRTonline.org

Genetic signatures that could predispose people to aortic stenosis (AS), and which could be most relevant to predicting thoracic aortic aneurysm, have been defined by researchers on a large UK population-based biobank.

Meta-Analysis Highlights Contrast Between RCT, Real-World Results for PCI in CTO Patients

Jul 19, 2022 by
Nathan Gray, CRTonline.org

Current evidence on the safety and efficacy of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) procedures from randomized controlled trials (RCTs) may not be representative of real-world patients and should be interpreted with caution, according to a new meta-analysis of data.

Chinese Study: Subintimal Plaque Modification with Guidewire Crossing Linked to Higher Success Rates in Repeat CTO PCI

Jul 18, 2022 by
Nathan Gray, CRTonline.org

Investment in subintimal plaque modification (SPM) with guidewire (GW) crossing – a process that plans for subsequent reattempts during an initial chronic total occlusion (CTO) percutaneous coronary intervention (PCI) procedure – is associated with a higher success rate in later reattempts, a new analysis shows.

Study: Updated PROGRESS-CTO Complication Score Provides Wider Risk Analysis for CTO PCI

Jul 18, 2022 by
Nathan Gray, CRTonline.org

New complication risk scores developed after wider updated analysis of data from the PROGRESS-CTO trial could help to better estimate the risks of periprocedural complications in patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI), say those behind the new scores.

International Experts Agree on 25 Standalone Criteria for Specialist Palliative Care Referral in Advanced HF

Jul 18, 2022 by
Natalie Morrison, CRTonline.org

International experts have agreed on 25 criteria for the referral of advanced heart failure patients to specialist palliative care in a new Delphi study.

2 Phenotypes of Fulminant COVID-19-Related Myocarditis Identified in French Study

Jul 18, 2022 by
Natalie Morrison, CRTonline.org

Two distinct phenotypes of patients with sudden and severe COVID-19-related myocarditis have been identified in a new retrospective analysis of French intensive care unit (ICU) patients without a history of COVID-19 vaccination.

Post-EVT Elevated Lp(a) Levels in PAD Patients Linked to Cardiovascular and Limb Risks: Japanese Study

Jul 18, 2022 by
Natalie Morrison, CRTonline.org

Lipoprotein(a) (Lp[a]) levels elevated above 30 mg/dL were independently associated with future cardiovascular and limb events in peripheral artery disease patients even after endovascular therapy (EVT), according to a new Japanese observational study.

Novel Approach to Define SCAI Cardiogenic Shock Stages Could Improve Clinical Application of the System, Say Registry Researchers

Jul 11, 2022 by
Natalie Morrison, CRTonline.org

A novel “structured clinically actionable framework” for defining Society for Cardiovascular Angiography and Interventions (SCAI) stages of cardiogenic shock (CS) severity was proposed Monday, based on a study of one of the largest multicenter CS registries in the U.S.

Early Subclinical Atherosclerosis May Drive Disparities in CVD Risk for Non-Hispanic Black People: Study Data

Jul 11, 2022 by
Nathan Gray, CRTonline.org

Non-Hispanic Black individuals are affected by atherosclerosis earlier in life and more severely than people of other racial and ethnic groups, potentially contributing to disparities in cardiovascular outcomes, a new analysis of real-world data suggests.

Systemic Thromboxane Generation Associated with All-Cause and CV Death, Irrespective of Aspirin Use

Jul 11, 2022 by
Nathan Gray, CRTonline.org

Systemic thromboxane generation is an independent risk factor for all-cause and cardiovascular mortality irrespective of aspirin use, according to a new analysis of Framingham Heart Study data.

Early Revascularization Associated with Survival Benefit in Patients with Normal LVEF and Severe Inducible Myocardial Ischemia

Jul 11, 2022 by
Nathan Gray, CRTonline.org

Early myocardial revascularization was associated with a significant reduction in mortality among both patients with normal left ventricular ejection fraction (LVEF) and severe inducible myocardial ischemia and patients with low LVEF and moderate or severe inducible myocardial ischemia, a new analysis suggests.

Study: DES Strut Thickness Does Not Impact Clinical Outcomes with Intravascular Imaging Guidance

Jul 05, 2022 by
Nathan Gray, CRTonline.org

Strut thickness differences among drug-eluting stents (DES) have little impact on clinical outcomes of percutaneous coronary intervention (PCI) when implanted with intravascular imaging guidance, new trial data from Japan report.

Trial Backs Mavacamten to Reduce Need for Septal Reduction Therapy in Patients with Obstructive HCM

Jul 05, 2022 by
Nathan Gray, CRTonline.org

Mavacamten significantly reduced the number of obstructive hypertrophic cardiomyopathy (oHCM) patients meeting guideline criteria for septal reduction therapy (SRT) after 16 weeks, new trial data reveal.

Two-Stent Approach Provides Benefit Over Provisional Stenting for Complex Coronary Bifurcation Lesions: 3-Year Data

Jul 05, 2022 by
Nathan Gray, CRTonline.org

At 3-year follow-up, a two-stent approach to complex coronary bifurcation lesions was associated with less target lesion failure (TLF), target vessel myocardial infarction (TVMI) and target lesion revascularization (TLR) compared to provisional stenting (PS); however, the benefits were seen solely in year 1, new trial data report.

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CRT Group Foundation is a not for profit corporation dedicated to providing educational services in the field of cardiology through the website, CRTonline.org and the Cardiovascular Research Technologies (CRT) annual symposium. CRT focuses on the advances and changes in the field of cardiovascular medicine. CRT is designed to provide access to the world’s leading clinicians and the latest research in order to improve practice and treatment outcomes for a variety of health care professionals.

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