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Novel Drug-Coated Balloon Saw Lower In-Lesion LLL vs. Drug-Eluting Stent in PICCOLETO II Trial

Nov 25, 2020 by
Natalie Morrison, CRTonline.org

The novel Elutax SV drug-coated balloon (DCB) resulted in significantly lower in-lesion late lumen loss (LLL) for small-vessel coronary artery disease (SVD) patients than the Xience everolimus-eluting stent in the European PICCOLETO II trial.

Obese COVID-19 Patients Face Higher Risk, Systemic Racism Evident, AHA COVID-19 Cardiovascular Registry Shows

Nov 17, 2020 by
Natalie Morrison, CRTonline.org

Clear public messages should warn of higher risk for obese COVID-19 patients, while more must be done to tackle the endemic issue of systemic racism in the U.S., researchers urged Tuesday, stressing that both obese and minority patients have fared worse in the American Heart Association’s (AHA) COVID-19 Cardiovascular Disease Registry.

Boston Scientific Recalls, Retires Lotus Edge Aortic Valve System

Nov 17, 2020 by
Jason Wermers, CRTonline.org

Boston Scientific announced Tuesday that it has begun a voluntary global recall of its Lotus Edge Aortic Valve System, and retired the entire product line, because of problems associated with its delivery system.

CT Coronary Angiography in Intermediate-, High-Risk Patients Fails to Improve Outcomes in Emergency Department, Study Shows

Nov 16, 2020 by
Giorgio A. Medranda, CRTonline.org

Early computed tomography coronary angiography (CTCA) in intermediate- or high-risk patients presenting to the emergency department with suspected or provisionally diagnosed acute coronary syndrome (ACS) did not impact overall treatment or prevention of ACS but was associated with a modest increase in length of stay and healthcare costs, according to late-breaking trial results presented Monday at the American Heart Association Scientific Sessions 2020 virtual conference.

THALES: Ipsilateral Atherosclerotic Stenosis a Marker for Better 30-Day Ticagrelor Stroke Outcomes

Nov 16, 2020 by
Natalie Morrison, CRTonline.org

A subgroup analysis of the THALES trial showed that ticagrelor added to aspirin reduced the 30-day risk of recurrent stroke by 27% in transient ischemic attack (TIA) and minor ischemic stroke patients with ipsilateral atherosclerotic stenosis of cervicocranial vasculature.

TAVR Use Exceeds That of SAVR in US in 2019, Outcomes Continue to Improve

Nov 16, 2020 by
Natalie Morrison, CRTonline.org

The number of transcatheter aortic valve replacement (TAVR) procedures exceeded all forms of surgical aortic valve replacement (SAVR) in the U.S. for the first time in 2019, while TAVR’s mortality and stroke rates continued to fall since the first approval in 2011.

Researchers: CT Screening Against Coronary Obstruction Should Be Performed Before Redo TAVR

Nov 16, 2020 by
Natalie Morrison, CRTonline.org

Pre-procedural computed tomography (CT) screening should be performed for “redo” transcatheter aortic valve replacement (TAVR) cases, particularly for patients with low sinotubular junction (STJ) height, researchers urged in a study released Monday.

Active ‘Mobile Health’ ECG Screening for Afib Associated with Better Cardiovascular Outcomes – New 3-Year Data

Nov 16, 2020 by
Natalie Morrison, CRTonline.org

An analysis of 3-year clinical outcomes in a U.S. “digital” clinical trial for atrial fibrillation (AF) screening trial to prevent strokes – the mSToPS study – showed active screening was associated with significantly improved stroke and death rates compared to standard-of-care.

1-Month DAPT Regimen Noninferior to Standard DAPT After PCI, Study Shows

Nov 15, 2020 by
Brian C. Case and Jason Wermers, CRTonline.org

A short, 1-month treatment combining antiplatelet medication and aspirin followed by an aspirin-only regimen was as effective as a 6- to 12-month course of dual treatment at preventing death, myocardial infarction, stroke, bleeding or revascularization, according to late-breaking trial results presented Sunday at the American Heart Association Scientific Sessions 2020 virtual conference.

Novel Supreme DES Shows Results Comparable to Xience, Promus DES

Nov 15, 2020 by
Chava Chezar-Azerrad, CRTonline.org

A novel biodegradable-polymer-coated drug-eluting stent (DES) was found to be as safe and effective as the contemporary polymer-based DES in patients with acute coronary syndromes (ACS) and chronic coronary syndromes (CCS) undergoing percutaneous coronary intervention (PCI), according to late-breaking trial results presented Sunday at the American Heart Association Scientific Sessions 2020 virtual conference.

Study: Evinacumab Reduces LDL-C vs. Placebo in Patients with Refractory Hypercholesterolemia

Nov 15, 2020 by
Jason Wermers, CRTonline.org

Evinacumab, whether administered intravenously or subcutaneously, significantly reduced low-density lipoprotein cholesterol (LDL-C), by greater than 50% at the highest dose levels, as compared to placebo, and the drug was generally well-tolerated, according to late-breaking trial results presented Sunday at the American Heart Association Scientific Sessions 2020 virtual conference.

Patients Report Nearly as Many Symptoms from Placebo as from Statins, Study Shows

Nov 15, 2020 by
Jason Wermers, CRTonline.org

Patients really do feel side effects from statins, which can prompt them to stop taking the cholesterol-lowering medication. But a study presented Sunday at the American Heart Association Scientific Sessions 2020 virtual conference shows that patients experienced nearly as many symptoms while taking a placebo as they did while taking statins.

Omega-3 CA Medication Shows No More STRENGTH Than Placebo at Reducing Cardiac Events

Nov 15, 2020 by
Brian C. Case and Jason Wermers, CRTonline.org

A new fish oil medication (omega-3 carboxylic acids [CA]) did not reduce the risk of cardiac events as compared to placebo in those patients with existing heart disease or who were at high risk of heart disease due to other medical conditions, according to results from the STRENGTH trial presented Sunday at the American Heart Association (AHA) Scientific Session 2020 virtual conference.

Rivaroxaban, Warfarin Show Similar Safety, Efficacy for Patients with AFib and Bioprosthetic Mitral Valve

Nov 14, 2020 by
Jason Wermers, CRTonline.org

In the largest study to assess the safety and efficacy of direct oral anticoagulants in patients with atrial fibrillation and a bioprosthetic mitral valve, rivaroxaban demonstrated noninferiority to warfarin in the mean length of event-free survival time, according to late-breaking trial results presented Saturday at the American Heart Association Scientific Sessions 2020 virtual conference.

Observational Study: OCT and CMR Can Help Identify MINOCA and Its Mechanisms in Women

Nov 14, 2020 by
Jason Wermers, CRTonline.org

Using both optical coherence tomography (OCT) and cardiac magnetic resonance imaging (CMR) outperformed using only one of those modalities in identifying myocardial infarction with non-obstructive coronary artery disease (MINOCA) in women, according to late-breaking study results presented Saturday at the American Heart Association Scientific Sessions 2020 virtual conference.

ALPHEUS Does Not Support Routine Ticagrelor Use in Elective PCI

Nov 14, 2020 by
Charan Yerasi, CRTonline.org

Ticagrelor is not superior to clopidogrel in reducing periprocedural ischemic events during elective percutaneous coronary intervention (PCI) in stable patients, according to late-breaking-trial results presented Saturday at the American Heart Association (AHA) Scientific Sessions 2020 virtual conference.

Regular Beta-Blocker Use Associated with Better Peripartum Cardiomyopathy Outcomes in Nigerian Study

Nov 09, 2020 by
Natalie Morrison, CRTonline.org

Regular use of beta-blockers was associated with better outcomes for women with peripartum cardiomyopathy (PPCM) in a 244-patient study in Nigeria, the country with the world’s highest incidence of the pregnancy complication.

European Registry Data: STEMI PPCI Procedures Fell While Mortality Rates Rose During COVID-19 Pandemic

Nov 09, 2020 by
Natalie Morrison, CRTonline.org

The ongoing COVID-19 pandemic has seen a significant reduction in the number of ST-segment elevation myocardial infarction (STEMI) patients receiving primary percutaneous coronary intervention (PPCI) treatment, according to a retrospective European registry analysis.

Wide Post-Valve Surgery Variation in Anticoagulation Practice Between US Centers Should Be Better Standardized – Database Researchers

Nov 09, 2020 by
Natalie Morrison, CRTonline.org

Anticoagulation practice continues to vary on a center-by-center basis in the U.S. following aortic and mitral valve replacement and repair surgeries, according to a database analysis.

Volumetric Echocardiographic Parameters Predict Mortality in Aortic Regurgitation, Study Reports

Nov 09, 2020 by
Giorgio A. Medranda, CRTonline.org

In patients with asymptomatic but hemodynamically significant aortic regurgitation (AR), left ventricular end-systolic volume index (LVESVi) and volume-derived left ventricular ejection fraction (Vol-LVEF) were found to predict mortality, according to recently released study results.

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CRT Group Foundation is a not for profit corporation dedicated to providing educational services in the field of cardiology through the website, CRTonline.org and the Cardiovascular Research Technologies (CRT) annual symposium. CRT focuses on the advances and changes in the field of cardiovascular medicine. CRT is designed to provide access to the world’s leading clinicians and the latest research in order to improve practice and treatment outcomes for a variety of health care professionals.

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