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8-Year Real-World Data in 5 Million Show ISR Makes Up Around 10% of PCIs

Sep 21, 2020 by
Natalie Morrison, CRTonline.org

A retrospective analysis of 8 years of real-world data from more than 5 million patients found that in-stent restenosis (ISR) represents approximately 10% of all percutaneous coronary intervention (PCI), 25% of whom presented with related myocardial infarction (MI).

First Short-Term Follow-Up of Mistral Tricuspid Valve Repair Finds Significant Improvement in Severe TR

Sep 21, 2020 by
Natalie Morrison, CRTonline.org

A short-term follow-up of the first-in-human study for the Mistral tricuspid valve repair device found that patients with severe tricuspid regurgitation (TR) – a group with no standard-of-care options – had significant improvements in their condition.

Study Identifies 2 Predictors of Effective Suture-Mediated Patent Fossa Ovalis Closure

Sep 21, 2020 by
Brian C. Case, CRTonline.org

Two simple parameters obtained from pre-procedural transesophageal echocardiogram (TEE) assessment, namely patent fossa ovalis (PFO) width >5 mm and spontaneous large right-to-left shunt (RLS), are associated with a lower probability of effective closure with only one stitch, according to a study released Monday.

Residual Coronary Artery Disease Impacts Mortality Following MitraClip, Study Reports

Sep 21, 2020 by
Giorgio A. Medranda, CRTonline.org

Residual coronary artery disease (CAD), as assessed by the SYNTAX score, following treatment of degenerative and functional mitral regurgitation (MR) with transcatheter mitral valve repair (TMVr) using the MitraClip, was associated with worse mortality at 1 year, according to a study released Monday.

Outcomes Worse in TAVR with Valvular Atrial Fibrillation, a Study Reports

Sep 21, 2020 by
Giorgio A. Medranda, CRTonline.org

The presence of valvular atrial fibrillation (AF) confers an increased risk of cardiovascular death or disabling stroke in patients undergoing transcatheter aortic valve replacement (TAVR), according to a prospective registry.

Sentinel CPS Shows Lower Risk of Stroke Post-TAVR, NIS Analysis Shows

Sep 21, 2020 by
Chava Chezar-Azerrad, CRTonline.org

The use of the Sentinel cerebral protection system (CPS) in patients during transcatheter aortic valve replacement (TAVR) showed better outcomes than in patients in whom the device was not used, according to a new analysis of the Nationwide Inpatient Sample database.

Non-recommended DOAC Dosing Associated with Higher Mortality Risk, Study Shows

Sep 15, 2020 by
Charan Yerasi, CRTonline.org

A new study from the GARFIELD-AF registry shows that patients who received non-recommended dosing of direct oral anticoagulants (underdosage and overdosage combined) were noted to have higher mortality than patients who received standard dosing.

CABG Beats PCI in Composite Outcome for Patients with LM Disease, at Least Moderate LV Dysfunction, Registry Analysis Shows

Sep 14, 2020 by
Jason Wermers, CRTonline.org

A registry analysis shows inferior results in the composite outcome of death, myocardial infarction or stroke for percutaneous coronary intervention (PCI) as compared to coronary artery bypass grafting (CABG) in patients with moderate or severe left ventricular (LV) dysfunction at baseline, but no difference between PCI and CABG in LMCA patients with mild LV dysfunction at baseline.

Higher LDL-C Following PCI Is Associated with Increased Cardiovascular Events, Study Reports

Sep 14, 2020 by
Giorgio A. Medranda, CRTonline.org

Higher low-density lipoprotein cholesterol (LDL-C) following percutaneous coronary intervention (PCI) is measured infrequently and associated with higher rates of cardiovascular death, myocardial infarction (MI), coronary revascularization, and stroke, a new study reports.

Progression to ESRD Following Balloon-Expandable TAVR Is Rare in CKD Patients

Sep 14, 2020 by
Giorgio A. Medranda, CRTonline.org

In extreme-, high- and intermediate-risk patients with chronic kidney disease (CKD) undergoing transcatheter aortic valve replacement (TAVR) using balloon-expandable transcatheter heart valves (THV), progression to end-stage renal disease (ESRD) requiring hemodialysis (HD) is extremely rare follow TAVR.

Small Study Shows CMR May Help Risk-Stratify Athletes Who Recover from COVID-19

Sep 11, 2020 by
Brian C. Case, CRTonline.org

Cardiac magnetic resonance (CMR) may provide an excellent risk stratification assessment for myocarditis in competitive athletes who have recovered from COVID-19, which could guide safe competitive sports participation, according to a study released Friday . These findings were published online Friday in JAMA Cardiology.

MitraClip Can Improve Outcomes in Patients with Both Mitral and Tricuspid Regurgitation, Study Shows

Sep 10, 2020 by
Natalie Morrison, CRTonline.org

In an analysis of patients from the COAPT trial with severe mitral regurgitation (MR) who have heart failure and tricuspid regurgitation (TR), treatment with MitraClip plus guideline-directed medical therapy (GDMT) led to more favorable prognoses compared to GDMT alone.

Complete Revascularization Benefits STEMI Patients with Most Severe Nonculprit Lesions, Study Shows

Sep 09, 2020 by
Natalie Morrison, CRTonline.org

An analysis of patients with ST-segment elevation myocardial infarction (STEMI) and multivessel coronary artery disease in the COMPLETE trial showed that those with more severe stenosis of nonculprit lesions gained bigger benefits from complete revascularization, in terms of cardiovascular outcomes.

Restrictive Blood Transfusion Noninferior to Liberal Strategy, Potentially Cost-Saving, in Acute MI

Sep 01, 2020 by
Jason Wermers, CRTonline.org

Using a more restrictive blood transfusion strategy is noninferior to a liberal transfusion strategy in treating anemic patients with acute myocardial infarction (MI) and is likely to save both money and blood, according to trial results presented Tuesday at the European Society of Cardiology (ESC) 2020 virtual congress.

Education on Stroke Prevention Does Not Increase Oral Anticoagulation Use in AFib Patients

Sep 01, 2020 by
Chava Chezar-Azerrad, CRTonline.org

Educating patients with atrial fibrillation who are at risk for stroke did not increase their overall use of oral anticoagulation (OAC), the IMPACT-AFib study shows.

ACE Inhibitors and ARBs Safe in COVID-19, Study Finds

Sep 01, 2020 by
Brian Forrestal, CRTonline.org

Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) are safe for use in patients with COVID-19, according to a study presented Tuesday at the European Society of Cardiology (ESC) 2020 virtual congress.

Ticagrelor Increases Risk of Death, Bleeding vs. Clopidogrel in Elderly ACS Patients, SWEDEHEART Analysis Shows

Sep 01, 2020 by
Jason Wermers, CRTonline.org

Ticagrelor and clopidogrel showed no difference in composite outcomes when used to treat elderly patients with acute coronary syndrome (ACS), but ticagrelor was associated with an increased risk of death and readmission for bleeding at 1 year after the index ACS admission, according to study results presented Tuesday at the European Society of Cardiology (ESC) 2020 virtual congress.

Ticagrelor Plus Aspirin Lowers Risk of Adverse Limb Events in Patients with Diabetes, CAD, PAD

Sep 01, 2020 by
Jason Wermers, CRTonline.org

Adding ticagrelor to aspirin for patients with diabetes, coronary artery disease (CAD) and peripheral artery disease (PAD) without a history of myocardial infarction (MI) or stroke lowers the risk of adverse limb events, according to study results presented Tuesday at the European Society of Cardiology (ESC) 2020 virtual congress.

HOME-PE Results Support Outpatient Care of Select Pulmonary Embolism Patients

Aug 31, 2020 by
Brian C. Case, CRTonline.org

For outpatient care of normotensive patients with acute pulmonary embolism (PE), the triaging strategy based on the pragmatic rule, Hestia, was noninferior to the strategy based on the severity risk assessment score, simplified Pulmonary Embolism Severity Index (sPESI), with respect to the composite endpoint of recurrent venous thromboembolism, major bleeding and death.

LoDoCo2: Colchicine Reduces Risk of Major Cardiovascular Events in Chronic Coronary Disease

Aug 31, 2020 by
Brian C. Case, CRTonline.org

Colchicine reduces the risk of major cardiovascular events in patients with chronic coronary disease, according to results from the LoDoCo2 trial.

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