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Continuous-Flow LVADs Increase Aortic Fibrosis and Stiffening: Study

Oct 25, 2021 by
Nathan Gray, CRTonline.org

The use of continuous-flow (CF) left ventricular assist devices (LVADs) increases the risk of patients developing aortic fibrosis and stiffening, and may contribute to the risks of hypertension, stroke and ventricular failure, new research suggests.

Target Higher Intraoperative Blood Pressure Does Not Reduce Post-Operative Risk: Swiss RCT

Oct 25, 2021 by
Natalie Morrison, CRTonline.org

Targeting higher intraoperative blood pressures does not reduce postoperative complications in at-risk patients undergoing noncardiac surgery, a new Swiss single-center randomized controlled trial (RCT) concluded.

Drug-Coated Devices May Provide Benefits in Peripheral Artery Disease: Study

Oct 25, 2021 by
Nathan Gray, CRTonline.org

The use of paclitaxel drug-coated devices (DCDs) in patients undergoing lower-extremity revascularization (LER) is associated with reduced need for unplanned repeated LER procedures and is not associated with risk of mortality or major adverse events, a post hoc analysis of trial data shows.

TEER and TMVR Procedures and Favorable Outcomes on the Rise in the US

Oct 25, 2021 by
Natalie Morrison, CRTonline.org

Transcatheter edge-to-edge repair (TEER) and transcatheter mitral valve replacement (TMVR) procedures have grown drastically in the U.S. since 2014, with improving outcomes over time, according to new data from the ongoing real-world Transcatheter Valve Therapy (TVT) Registry.

RV Dysfunction Linked to Higher Rate of 2-Year Adverse Outcomes in Patients with Secondary MR

Oct 18, 2021 by
Nathan Gray, CRTonline.org

Right ventricular (RV) dysfunction, as evidenced by ventricular-arterial uncoupling, is “strongly and independently” associated with 2-year adverse outcomes in patients with heart failure (HF) and secondary mitral regurgitation (SMR), according to a new analysis of trial data.

Racial, Ethnic and Sex-Based Discrimination Still Pervasive in Cardiology, ACC Survey Finds

Oct 18, 2021 by
Natalie Morrison, CRTonline.org

Racial and ethnic minority cardiologists are underrepresented in the workforce, and continue to face discrimination and missing representation, analyses of the American College of Cardiology’s (ACC) 2015 Professional Life Survey show.

Transcatheter Mitral Valve Repair Has ‘Significant’ Benefit for 1-Year Hospitalizations

Oct 18, 2021 by
Nathan Gray, CRTonline.org

Transcatheter mitral valve repair (TMVr) has a “significant and sustained” effect in reducing both all-cause and heart failure (HF)-related hospitalizations 1 year after procedure compared with the year prior, analysis of new population data reports.

Systolic and Diastolic Blood Pressure Targets May Need Modification to Suit Specific Cardiovascular Risk – ALLHAT Analysis

Oct 18, 2021 by
Natalie Morrison, CRTonline.org

Blood pressure targets for both systolic blood pressure (SBP) and diastolic blood pressure (DBP) may need to be modified depending on the cardiovascular outcome for which the patient is most at risk.

Cardiovascular Disease Fellowship Program Directors Report High Stress and Burnout Rates – Survey

Oct 18, 2021 by
Natalie Morrison, CRTonline.org

Stress and burnout remain common issues among directors of cardiovascular disease fellowship programs, particularly for women, early-career directors and those in charge of larger, university-based programs, a survey has found.

Isolated Transcatheter Tricuspid Valve Repair Shows Benefits for TR: Meta-Analysis

Oct 18, 2021 by
Nathan Gray, CRTonline.org

Isolated transcatheter tricuspid valve repair (ITTVR) may offer significant benefits for patients with tricuspid regurgitation (TR), according to a new meta-analysis of clinical studies.

Atherosclerotic Disease Risk Factors Can Guide First Coronary Artery Calcium Scan Timing in Young Adults – CAC Consortium Analysis

Oct 11, 2021 by
Natalie Morrison, CRTonline.org

Risk factor profiles for atherosclerotic cardiovascular disease (ASCVD), including diabetes, smoking, hypertension, dyslipidemia and family history, can be used to determine the recommended age for a first coronary artery calcium (CAC) scan in young adults to determine those susceptible for premature disease, a new CAC Consortium analysis of has found.

SCN5A Identified as a Major Susceptibility Gene in J-Wave Syndromes

Oct 11, 2021 by
Nathan Gray, CRTonline.org

Analysis of patients with two major forms of inherited J-wave syndrome (JWS) has uncovered novel variants of the SCN5A gene associated with different forms.

Clinical Advantage: Stress CMR Backed for Larger Role in Evaluating Ischemic Heart Disease

Oct 11, 2021 by
Nathan Gray, CRTonline.org

Given its clinical advantages, lack of ionizing radiation, and cost-effectiveness, stress cardiovascular magnetic resonance imaging (CMR) is expected to be increasingly used for evaluating ischemic heart disease, a new review concludes.

Machine Learning Study Boosts Proteomics-Based Risk Estimates

Oct 11, 2021 by
Nathan Gray, CRTonline.org

Machine learning (ML) driven risk models based on multi-protein proteomics outperform classical regression models and clinical scores for prediction of all-cause mortality in patients at increased cardiovascular risk, according to new research.

Diabetics with Cardiomyopathy at High Risk of Heart Failure Regardless of Heart Disease Definition – U.S. Cohort Analysis

Oct 11, 2021 by
Natalie Morrison, CRTonline.org

Diabetes with cardiomyopathy (DbCM) puts patients at high risk of developing heart failure, regardless of the criteria used to define cardiomyopathy, according to a new analysis of subjects from three U.S. cohort studies.

Lipid-Modulating Treatments Could Mitigate COVID-19 Effects Through Anti-Inflammatory, Antiviral and Pleiotripic Mechanisms: Review

Oct 11, 2021 by
Natalie Morrison, CRTonline.org

Lipid-modulating therapies could mitigate COVID-19-associated multiorgan damage through anti-inflammatory, antiviral and pleiotropic effects, experts wrote in a review paper as they await results from dozens of trials to this end.

Novel Algorithm May Guide Revascularization Practice in Patients with Coexisting AS and CAD

Oct 05, 2021 by
Nathan Gray, CRTonline.org

Decisions regarding coronary revascularization of patients with coexisting aortic stenosis (AS) and coronary artery disease (CAD) should be based on understanding this complex relationship, using appropriate coronary assessment and consensus within a multidisciplinary team, say the authors of a new review.

Bigger Is Better: Oversizing THV Improves Hemodynamics and Lowers PVR Incidence

Oct 04, 2021 by
Nathan Gray, CRTonline.org

In patients with annular dimensions suitable for two valve sizes, implantation of a larger SAPIEN 3 transcatheter heart valve (THV) oversized to both annular area and perimeter was associated with lowest incidence of paravalvular regurgitation (PVR) and improved hemodynamics, reports a new analysis from the PARTNER 3 trial.

Real-World US TAVR Outcomes Similar to RCTs in First Study to Estimate Standard Practice Treatment Effects

Oct 04, 2021 by
Natalie Morrison, CRTonline.org

Real-world outcomes for transcatheter aortic valve replacement (TAVR) patients are likely similar to those observed in randomized controlled trials (RCTs), despite some key differences in important baseline characteristics between those treated in trial and clinic, researchers comparing U.S. CoreValve trial results with Medicare data said.

Bicuspid TAVR Shows Similar 1-Year Survival to Tricuspid TAVR, But May Carry Complication Risk

Oct 04, 2021 by
Nathan Gray, CRTonline.org

Transcatheter aortic valve replacement (TAVR) is a feasible option among selected patients with bicuspid aortic valve (BAV) anatomy, but increased risk of complications warrants “caution and further evidence,” according to meta-analysis of trial data.

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CRT Group Foundation is a not for profit corporation dedicated to providing educational services in the field of cardiology through the website, CRTonline.org and the Cardiovascular Research Technologies (CRT) annual symposium. CRT focuses on the advances and changes in the field of cardiovascular medicine. CRT is designed to provide access to the world’s leading clinicians and the latest research in order to improve practice and treatment outcomes for a variety of health care professionals.

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