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Radiation Risks in Pregnancy, SCAD Diagnosis Challenges Among Topics Spotlighted at Women in Interventional Cardiology Session

Mar 04, 2021 by
Matthew Litman, CRTonline.org

CRT 2021 Virtual’s Women in Interventional Cardiology Focused Session covered a variety of topics, including the risks of radiation exposure for pregnant patients and physicians, sex disparities in management of cardiogenic shock and the difficulty of diagnosing spontaneous coronary artery dissection.

FDA Town Hall Keynote Speaker: ‘Almost All’ Clinical Trials Affected by COVID-19

Mar 03, 2021 by
Matthew Litman, CRTonline.org

COVID-19’s impact on clinical trials has been vast and far-reaching. Dominic Allocco, MD, MS, of Boston Scientific, said that “almost all” clinical trials were impacted by COVID-19. He was the keynote speaker Friday during CRT 2021 Virtual’s FDA Town Hall.

IVL: A Simpler New Option for Complex Calcified Lesions, But Will Reimbursement Prohibit Uptake?

Mar 02, 2021 by
Natalie Morrison, CRTonline.org

The recent U.S. approval of intravascular lithotripsy (IVL) means a simpler new treatment option for certain types of calcified lesions – one of the most complex lesions in interventional cardiology – according to key opinion leaders speaking with CRTonline.org.

COVID-19 Affects Structural Heart Disease Research

Mar 01, 2021 by
Jason Wermers, CRTonline.org

The COVID-19 pandemic’s disruptions have left virtually no area untouched, and that includes research into valve and structural heart disease. Presenters detailed those effects in the Landmark Session during Week 3 of CRT 2021 Virtual on Saturday.

ACC Scientific Session to Be All Virtual Once Again

Feb 24, 2021 by
CRTonline.org

The American College of Cardiology (ACC) Scientific Sessions 2021 will be held completely online, marking the second consecutive year that the meeting will be virtual.

VERDICT Analysis: Coronary Computed Tomography is ‘Equivalent’ to Invasive Coronary Angiography in NSTEACS Risk Stratification

Feb 22, 2021 by
Natalie Morrison, CRTonline.org

Coronary computed tomography angiography (CTA) was as effective as invasive coronary angiography (ICA) for predicting long-term risk in patients with non–ST-segment elevation acute coronary syndrome (NSTEACS), according a 4-year follow-up analysis of the Danish VERDICT trial.

3-Year COAPT Follow-Up Shows Sustained MitraClip Benefits

Feb 22, 2021 by
Natalie Morrison, CRTonline.org

Heart failure (HF) patients with functional mitral regurgitation (MR) given transcatheter mitral valve repair (TMVr) with MitraClip continued to see benefits over those on guideline-directed medical therapy (GDMT) alone at 36 months in the COAPT study.

More Aggressive Cardiovascular Disease Preventative Strategies Needed For Women With History of Hypertensive Disorders of Pregnancy – Researchers

Feb 22, 2021 by
Natalie Morrison, CRTonline.org

Women with histories of hypertensive disorders of pregnancy (HDP), including pre-eclampsia and gestational hypertension, saw pronounced differences in heart structure and function a decade after pregnancy, according to the authors of a 132-subject study.

PE, but Not DVT, After TAVR Associated With Higher In-Hospital Mortality Risk

Feb 22, 2021 by
Jason Wermers, CRTonline.org

Pulmonary embolism (PE) was associated with an increased risk of in-hospital mortality when it happens after transcatheter aortic valve replacement (TAVR), but the same is not true of deep vein thrombosis (DVT), according to an analysis presented Friday at CRT 2021 Virtual.

BIOFLEX-I: Astron Pulsar, Pulsar-18 Stents Safe, Effective in Peripheral Disease at 3 Years

Feb 20, 2021 by
Jason Wermers, CRTonline.org

The Astron Pulsar and Pulsar-18 self-expanding nitinol stents are safe and effective for treatment of lesions in the superficial femoral artery (SFA) and proximal popliteal artery (PPA), with good clinical and quality-of-life results at 3 years, according to study results presented Friday at CRT 2021 Virtual.

Prehospital Crushed Prasugrel Did Not Improve Early Reperfusion Markers in STEMI Patients vs. Whole Tablets, Analysis Shows

Feb 20, 2021 by
Jason Wermers, CRTonline.org

Crushed prasugrel given to ST-elevation myocardial infarction (STEMI) patients in the ambulance did not lead to significantly improved markers for early reperfusion as compared to non-crushed prasugrel, according to an analysis presented Friday at CRT 2021 Virtual.

Retrospective Study: Cangrelor Reduces Ischemic Events Without Increasing Bleeding vs. GPI in PCI

Feb 19, 2021 by
Jason Wermers, CRTonline.org

Cangrelor reduced ischemic events without increasing bleeding as compared to glycoprotein IIb/IIIa inhibitors (GPIs) in patients undergoing percutaneous coronary intervention (PCI), according to a single-center study presented Friday at CRT 2021 Virtual.

Disrupt CAD III Substudy: Shockwave IVL Safe, Effective in Both Short and Long Severely Calcified Coronary Lesions

Feb 19, 2021 by
Jason Wermers, CRTonline.org

The Shockwave intravascular lithotripsy (IVL) system handled long severely calcified coronary lesions with the same safety and efficacy as shorter severely calcified coronary lesions, according to an analysis presented Friday at CRT 2021 Virtual.

FDA Panel Says Lutonix 014 DCB Is Safe but Not Effective for BTK CLI

Feb 17, 2021 by
Jason Wermers and Brian C. Case, CRTonline.org

A U.S. Food and Drug Administration advisory panel recommended against premarket approval of the Lutonix 014 drug-coated balloon (DCB) to treat below-the-knee (BTK) critical limb ischemia (CLI) after a daylong virtual meeting Wednesday.

In PCI Patients, Low HbA1c Tied to Increased Death Risk; High HbA1c Associated with MI Risk

Feb 15, 2021 by
Jason Wermers and Chava Chezar-Azerrad, CRTonline.org

Preprocedural glycated hemoglobin (HbA1c) levels indicate a greater risk for death after percutaneous coronary intervention (PCI) in patients with low HbA1c levels (≤5.5%) and higher risk for myocardial infarction (MI) with higher HbA1c levels (>8%), according to a large registry analysis released Monday.

Distal Radial Access Lowers Radial Artery Occlusion vs. Proximal Access, Study Shows

Feb 15, 2021 by
Brian C. Case, CRTonline.org

Distal radial access – also known as the “snuffbox approach” – prevents radial artery occlusion (RAO) in the proximal segment after the procedure in comparison with conventional radial access, according to a study released Monday.

Registry Researchers: Validated Management Strategies Needed ‘Urgently’ for Type 2 Myocardial Infarction as Unique Phenotype

Feb 15, 2021 by
Natalie Morrison, CRTonline.org

Clinical trials are “urgently needed” to define validated management strategies for type 2 myocardial infarction (MI), researchers on a registry study of more than 250,000 patients have stressed, after finding these patients have a unique cardiovascular phenotype from type 1 MI.

Radial to Femoral Access-Site Crossover in Invasive ACS Procedures Did Not Increase Risk in MATRIX Trial

Feb 15, 2021 by
Natalie Morrison, CRTonline.org

Access-site crossover from radial to femoral access in patients with acute coronary syndrome (ACS) undergoing invasive management did not appear to increase risk of major cardiovascular and clinical events in the MATRIX trial, despite a greater risk of bleeding.

Registry Analysis: Contralateral Carotid Occlusion is Risk Predictor in Carotid Endarterectomy, Despite Opposing Observational Data

Feb 15, 2021 by
Natalie Morrison, CRTonline.org

Contralateral carotid occlusion (CCO) remains an important predictor of worse in-hospital outcomes for patients undergoing carotid endarterectomy (CEA), despite recent studies calling the risk factor into question, according to a new U.S. registry study.

TICO-ACS Substudy: Ticagrelor Monotherapy After Short-Term DAPT Reduces Major Bleeding Events Without Increase in Ischemic Events in STEMI

Feb 15, 2021 by
Charan Yerasi, CRTonline.org

Ticagrelor monotherapy after short-term dual antiplatelet therapy (DAPT) reduces major bleeding events without increasing ischemic events in patients with ST-segment elevation myocardial infarction (STEMI), according to a substudy from the TICO ACS trial released Monday.

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