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  • PARADISE-MI Win-Ratio Analysis Shows Sacubitril/Valsartan Superior to Ramipril in Preventing CV Death or Heart Failure

    Analysis ‘may help to better understand, although not change’ trial’s neutral primary results, investigator says

    Sacubitril/valsartan was superior to ramipril among high-risk survivors of acute myocardial infarction (MI), according to a new post hoc win-ratio analysis of the PARADISE-MI randomized trial, even though the trial’s primary results showed no difference between the medications in cardiovascular death or incident heart failure.

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