A “precision” strategy of evaluating patients with chest pain for suspected coronary artery disease (CAD) with test deferral for low-risk patients and the use of cardiac computed tomography angiography (CCTA) in elevated-risk patients showed a 70% reduction in the composite of death, non-fatal myocardial infarction (MI) or catheterization without obstructive CAD compared to standard testing at 1 year, new trial results show.