With interest we read the article by Kong et al. about two SARS-CoV-2 infected patients with Takotsubo syndrome (TTS) complicated by cardiogenic shock [ ]. Patient-1 (88yo male with metastatic prostate cancer) deceased but patient-2 (79yo female with multiple sclerosis) recovered [ ]. It was concluded that TTS should remain on the differential in the setting of arrhythmias, systolic dysfunction, cardiac biomarker elevation, or ST-elevation [ ]. We have the following comments and concerns.