Periprocedural Myocardial Injury: Pathophysiology, Prognosis, and Prevention
Highlights
- • Definitions of PMI are many and have evolved over recent years.
- • PMI can be caused by a variety of mechanisms that occur either independently or concurrently
- • PMI after coronary intervention might be associated with worse clinical outcomes
- • Several strategies have demonstrated cardioprotection properties in patients undergoing coronary intervention.
Abstract
The definition and clinical implications of myocardial infarction occurring in the setting of percutaneous coronary intervention have been the subject of unresolved controversy. The definitions of periprocedural myocardial infarction (PMI) are many and have evolved over recent years. Additionally, the recent advancement of different imaging modalities has provided useful information on a patients' pre-procedural risk of myocardial infarction. Nonetheless, questions on the benefit of different approaches to prevent PMI and their practical implementation remain open. This review aims to address these questions and to provide a current and contemporary perspective.