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  • Percutaneous Mitral Valve Repair Vs. Stand-Alone Medical Therapy in Patients with Functional Mitral Regurgitation and Heart Failure

    Highlights

    • Functional mitral regurgitation is a common finding among patients with heart failure and it is related to adverse events
    • Our meta-analysis show a statistically significant reduction in all-cause mortality favoring MitraClip
    • Our data show a significant reduction in heart failure hospitalizations and indication for advanced heart failure therapies
    • Our work supports the use of MitraClip in patients with functional mitral regurgitation and heart failure

    Abstract

    Background

    Functional mitral regurgitation (FMR) is a common finding among patients with heart failure (HF) and it is related to adverse events. Outcomes in patients undergoing transcatheter mitral valve repair (TMVR) are still a matter of debate. We performed a meta-analysis to assess mid- and long-term outcomes of patients with FMR treated with MitraClip® compared to medical management.

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