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  • Outcomes with Drug-Coated Balloons in Percutaneous Coronary Intervention in Diabetic Patients

    Highlights

    • Percutaneous coronary intervention in patients with diabetes mellitus remains associated with inferior clinical outcomes with non-diabetic patients even in the era of drug-eluting stents (DES).
    • We performed a meta-analysis of all published studies reporting the outcomes with drug-coated balloons (DCBs) vs. DES after de-novo coronary PCI in diabetic patients.
    • DCBs are associated with similar clinical and angiographic outcomes compared with first-generation DES in diabetic patients,
    • DCBs might be associated with a potential reduction in TLR, but this needs a large RCT powered to identify that benefit

    Abstract

    Background

    Percutaneous coronary intervention (PCI) in patients with diabetes mellitus (DM) remains associated with inferior clinical outcomes and an increased risk of restenosis compared with non-diabetics even in the era of drug-eluting stents (DES). The outcomes with drug-coated balloons (DCBs) in diabetic patients have received limited study.

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