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  • Editorial: Non-ST-Segment Elevation Myocardial Infarction Revascularization: Is ≤24 h Early Enough?

    Non-ST-segment elevation myocardial infarction (NSTEMI) is a heterogeneous disease that, unlike ST-segment elevation myocardial infarction (STEMI), quite often does not present with a diagnostic electrocardiogram (EKG). This can be due to the culprit lesion not being totally occluded or being a “silent” 100% blocked lesion, which is not evident on the EKG. In the setting in which the culprit coronary artery is not completely occluded, the blood flow may not be able to maintain the myocardium in a viable state. While the initial presentation of NSTEMI may not be as overt as that for STEMI, there is, nonetheless, a high incidence of adverse outcomes [  ]. The VERDICT study and the meta-analysis by Jobs et al. showed that in high-risk patients with a Global Registry of Acute Coronary Events (GRACE) score of ≥140, early revascularization (≤24 h) will result in improved outcomes [  ,  ].

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