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  • How should left ventricular function and other high-risk features influence selection of revascularization?

    At the beginning of this year, the long term mortality of the SYNTAX trial based on the left ventricular function was published in this journal [  ]. The current guidelines recommend coronary artery bypass grafting (CABG) over percutaneous coronary intervention (PCI) for multivessel disease patients with ejection fraction of less than 35 %. However, long term follow-up of multivessel and left main patients has not revealed the influence of left ventricular function on survival. Now with the 10-year follow-up of SYNTAX complete, the impact of left ventricular function was examined. The authors looked at three groups: those with preserved ejection fraction, defined as greater than 50 %; mildly reduced ejection fraction, as 40–49 %; and reduced ejection fraction of less than 40 %. Ten-year mortality was 22.6 % for those with preserved ejection fraction, 31.8 % for those with mildly reduced ejection fraction, and 44.0 % for the reduced ejection fraction group.

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