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  • Editorial: The Carillon Mitral Contour System: Another tool in the fight against functional mitral regurgitation

    Mitral regurgitation is the most common valvular abnormality in adults over the age of 55 years and is associated with significant morbidity and mortality [  ]. In contrast to primary mitral regurgitation which results from a defect in the leaflets themselves, functional mitral regurgitation (FMR) (also known as secondary mitral regurgitation) can be due to a variety of etiologies which distort the architecture surrounding otherwise normal mitral valve leaflets [  ]. More common causes include ischemic or nonischemic cardiomyopathy leading to left ventricular remodeling or mitral annular enlargement from left atrial dilation [  ]. As the cause of FMR varies, the potential solutions are similarly varied and should be tailored to each individual patient [  ]. Medical therapy is the foundation of treatment regardless of etiology as some patients can see a reduction in the severity of their FMR with medical therapy alone [  ]. In select patients, cardiac resynchronization therapy is also needed to achieve reverse remodeling and reduction in mitral regurgitation [  ]. However, when these tools are insufficient to improve regurgitation, other invasive options should be considered [  ].

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