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  • Clinical Challenges in an Unusual Setting: ST-Elevation in a Patient Suffering From Graft Versus Host Disease, Between Thrombosis and Coronary Spasm

    • Posted: 08/25/2021
    • Author:

      Gaetano Liccardo, Elena Corrada, Letizia Bertoldi, Martina Briani, Jorge Sanz-Sanchez, Mauro Chiarito, Jacopo Mariotti, Chiara de Philippis, Armando Santoro, Bernhard Reimers and Damiano Regazzoli

    • CRM2021

    1

    Case report

    We report the case of a 40 years-old man, with acute onset of oppressive chest pain during hospitalization for graft versus host disease (GVHD) after allogeneic bone marrow transplant from human leukocyte antigen (HLA)-identical donor for acute lymphoblastic leukemia. Electrocardiogram (ECG) showed marked ST-elevation in inferior derivations, mild ST-elevation in V5-V6 leads, together with ST depression in D1 and avL ( Fig. 1 A ); at the time of pain onset patient's heart rate was 100 beats per minute and his arterial pressure was 135/95 mmHg.

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