Chest pain early after percutaneous coronary interventions (PCIs) is a relatively common complaint [[1], [2], [3], [4]]. Nonetheless, structured criteria have not been established and guidelines regarding a practical approach are vague [5,6]. The etiologies of chest pain early after PCI are heterogeneous, leading to empiric management approach according to the subjective perception of this entity by the treating physician. In addition to clinical judgment, biomarkers and electrocardiogram (ECG) remain the traditional workup approach, and more objective evaluation by non-invasive or repeat invasive imaging is not commonly ensued. Although in most cases the symptoms are managed conservatively [7] and are not perceived as indicators of an acute event, chest pain after PCI may carry prognostic implications [3]. Subjective interpretation of such complaint's influences management strategies and outcomes, including reassurance of patients and their families.