In the present issue of Cardiovascular Revascularization Medicine, Dr. Haddad and colleagues report the results of the ACCURACY study ( NCT03815032 ), which compares pressure-wire drift in a single-center, prospective wire-to-wire comparative analysis. In this pilot study, 45 patients undergoing invasive wire-based physiologic assessment during cardiac catheterization were enrolled. The initial 30 patients had measurements performed using two optical sensor pressure wires (OSPWs) simultaneously, whereas the final 15 patients enrolled in the study had fractional flow reserve (FFR) measurements obtained from the simultaneous use of an OSPW and a piezoelectric pressure wire (PEPW). The second-generation OSPW, OptoWire Deux (Opsens Medical, Quebec, Canada), was the study device investigated in the ACCURACY study. The authors report that the OSPW had a high level of agreement with simultaneous recording with two OSPWs. They also conclude that OSPW is associated with a significantly lower rate of drift compared to a PEPW .