William Röntgen discovered X-rays in 1895, an accomplishment recognized by the 1st Nobel Prize in Physics. Rapid clinical adoption led to the early observation of X-ray-induced skin erythema, the first indication that radiation exposure (RE) was a “double-edged sword." It is now axiomatic that accumulated occupational RE predisposes health care personnel working in the fluoroscopic environment to serious occupational health hazards . RE induces direct adverse effects including documented prevalence of premature cataracts, as well as growing concerns for cancer induction. RE is also implicated in occupational “collateral damage,” the predilection to orthopedic injuries inextricably linked to the adverse effects of burdensome and only partly protective personal protective lead apparel (brain and extremities still exposed). These occupational risks impact not only the physician operators closest to “ground zero” of the X-ray source, but apply as well to the entire catheterization laboratory team, including nurses and technicians.