Regional registries serve many purposes. They provide insight into unique demographic issues that may be specific to the region. There may be esoteric challenges that arise, ranging from patient screening and consent to anatomical complexities and quality-of-life outcomes. Such registries provide information on the external validity for pivotal trials and serve as a comparison to the large registries in the United States and Europe. Lastly, they may provide insights into processes that may be adopted more widely to improve the patient experience and patient outcomes.