Heart disease and cancer are the leading causes of death among the US population . With a significant improvement in the overall survival among patients with ischemic heart disease and among patients with cancer, an overlap between these two diseases is becoming more common. These two diseases are additionally linked by common risk factors (diabetes, hypertension, tobacco use, sedentary lifestyle, hyperlipidemia, older age), cardiotoxic cancer therapies (radiation, antimetabolites, anti-microtubule agents, alkylators, platinum, anti-tumor antibiotics, vinca alkaloids, proteasome inhibitors, vascular endothelial cell growth inhibitors, BCR-ABL tyrosine kinase inhibitors), and cancer-related accelerated atherosclerosis .