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  • Editorial: Cerebral Embolic Protection for TAVR: Don't Let It Go to Your Head

    Transcatheter aortic valve replacement (TAVR) has begun to replace surgical AVR (SAVR) as the predominant modality for valve replacement in patients with severe aortic stenosis (AS). However, stroke remains a significant TAVR complication, with 30-day post-TAVR ischemic stroke rates of up to 6.7% reported in the pivotal TAVR device trials. Few risk factors for peri-TAVR stroke have been identified. A meta-analysis of 64 studies including 72,318 patients with 2385 (3.3%) strokes identified female sex, chronic kidney disease, new-onset atrial fibrillation, and early timing in a center's TAVR experience as stroke predictors, none of which are modifiable.

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