The whole is something else than the sum of its parts - Kurt Koffka Cardiovascular disease and cancer are currently the leading causes of morbidity and mortality in the United States [1] . Both conditions share overlapping risk factors – to include diabetes, smoking, obesity, hypertension, and physical inactivity. Cancer patients are at increased risk of cardiovascular mortality compared to the general non-cancer population [2] . A progressively aging population coupled with ongoing advances in cancer therapies portends growing numbers of older cancer patients with concomitant coronary artery disease (CAD), acute myocardial infarction (MI), and/or cardiac arrest (CA) [3] .