In patients with severe aortic stenosis, transcatheter aortic valve replacement (TAVR) has become an acceptable alternative therapeutic procedure to surgical aortic valve replacement (SAVR). Although TAVR is increasingly utilized in clinical practice, there are limited real-world peri-procedural data pertinent to coronary ischemic events and myocardial injury. Type I myocardial infarction (MI) has been associated with worse outcomes after TAVR [ ]. In modern clinical practice, type II MI is more common than type I MI and is associated with an overall worse short and long-term prognosis [ ]. Furthermore, TAVR candidates are usually older than their SAVR counterparts and have higher rates of comorbidities which may predispose them to an increased risk of myocardial oxygen demand-supply mismatch. Therefore, we sought to evaluate the clinical characteristics and outcomes of patients with type-2 MI in the setting of TAVR using a large national database.