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  • Assessment of Vascular Patency and Inflammation with Intravascular Optical Coherence Tomography in Patients with Superficial Femoral Artery Disease Treated with Zilver PTX Stents

    Highlights

    • Intravascular optical coherence tomography can measure features which are proxies for inflammatory response.
    • Zilver PTX stents show evidence of inflammatory response at 12 months.
    • Stent cross-sectional area increased over time even as the lumens narrowed over time.

     

    Abstract

    Purpose

    Zilver PTX nitinol self-expanding drug-eluting stent with paclitaxel coating is effective for treatment of superficial femoral artery (SFA) disease. However, as with any stent, it induces a measure of vascular inflammatory response. The current clinical trial ( NCT02734836 ) aimed to assess vascular patency, remodeling, and inflammatory markers with intravascular optical coherence tomography (OCT) in patients with SFA disease treated with Zilver PTX stents.

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