In the United States, transradial arterial access (TRA) is progressively being used more and more for patients undergoing diagnostic cardiac catheterization (CC) and percutaneous coronary intervention (PCI). A strong number of studies have demonstrated that use of TRA has its benefits over the transfemoral approach. Some of these benefits include reductions in the risk of access-related complications, vascular bleeding, and mortality, as well as reductions in cost and patient discomfort. As the number of physicians who use TRA grows, so do the efficacy and safety of the procedure. Studies that can further improve TRA techniques and standards of care are most relevant and impactful as we move toward preferring TRA procedures.