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ASSAIL-MI Trial: IL-6 Inhibition with Tocilizumab Increased Myocardial Salvage by 5.6% vs. Placebo in STEMI Patients

Apr 12, 2021 by
Natalie Morrison, CRTonline.org

The interleukin-6 (IL-6) inhibitor tocilizumab increased myocardial salvage by 5.6% versus placebo in ST-segment elevation myocardial infarction (STEMI) patients in the Norwegian ASSAIL-MI trial. The positive effects seemed to be limited to patients presenting more than 3 hours after symptom onset, however.

Taiwan Registry Study: Fluoroquinolones Carry Higher Risk in Aortic Dissection and Aneurysm Patients

Apr 12, 2021 by
Natalie Morrison, CRTonline.org

Fluoroquinolones carried higher risk of adverse outcomes in patients diagnosed with aortic dissection (AD) and aneurysm (AA) in a large Taiwanese cohort.

Korean Registry: New Approach Needed to Identify STEMI Late-Presenters Who Could Benefit from Interventional Procedures

Apr 12, 2021 by
Natalie Morrison, CRTonline.org

A new multidisciplinary approach is needed to identify late presenters of ST-segment elevation myocardial infarction (STEMI) who could benefit from invasive interventional procedures, researchers on a real-world Korean study have urged.

ProGlide, MANTA Debated During Large-Bore Access Closure Session at CRT

Apr 10, 2021 by
Jason Wermers, CRTonline.org

Suture-mediated closure of large-bore vascular access, such as with Perclose ProGlide (Abbott), “has emerged as the preferred technique,” Sahil A. Parikh, MD, said during a focused session on large-bore closure Saturday at CRT 2021 Virtual. Nicolas M. Van Mieghem, MD, PhD, advocated for collagen-based, or plug-based, closure devices, of which MANTA (Teleflex) is the first commercially available dedicated large-bore closure device in the U.S. and Europe.

Device Helps Father-Son Duo Make Quick Treatment Adjustment During CRT Live Case

Apr 06, 2021 by
Matthew Litman, CRTonline.org

Thanks to measurements provided by Abbott’s Coroventis CoroFlow Cardiovascular System, Richard Shlofmitz, MD, and his son, Evan Shlofmitz, DO, were able to adjust their plan of treatment on the fly during a recent live case at CRT 2021 Virtual.

TAVR Could Be Viable, Durable Option for Rheumatic AS vs. SAVR

Apr 05, 2021 by
Natalie Morrison, CRTonline.org

Transcatheter aortic valve replacement (TAVR), as opposed to surgical aortic valve replacement (SAVR), could be a viable and durable treatment option for patients with rheumatic aortic stenosis (AS), according to a new U.S. study.

Cardiac Cath Labs Can Treat Acute Ischemic Stroke Without Neurointerventionalists, Study Reports

Apr 05, 2021 by
Giorgio A. Medranda, CRTonline.org

A catheter-based thrombectomy program initiated in an experienced cardiac catheterization laboratory with close cooperation among cardiologists, neurologists and radiologists can yield outcomes comparable to those of established neuroradiology centers, according to results released Monday from the PRAGUE-16 study.

RE-DUAL PCI Post Hoc: Dabigatran Dual Therapy ‘Markedly’ Reduced Early Bleeding Risk in AFib Patients Undergoing PCI vs. Triple Warfarin Regimen

Apr 05, 2021 by
Natalie Morrison, CRTonline.org

The oral anticoagulant dabigatran plus a P2Y12 inhibitor was found to “markedly” reduce the risk of early bleeding in patients with nonvalvular atrial fibrillation undergoing percutaneous coronary intervention (PCI) compared to warfarin triple therapy, according to a new post hoc analysis funded by dabigatran manufacturer Boehringer Ingelheim.

SWEDEHEART Analysis: Uninterrupted Oral Anticoagulants Should Be ‘Preferred Strategy’ for PCI

Apr 05, 2021 by
Natalie Morrison, CRTonline.org

New findings from the SWEDEHEART registry suggest that uninterrupted oral anticoagulant (OAC) therapy should be the preferred strategy in patients on these medicines undergoing percutaneous coronary intervention (PCI).

Less DAPT Can Help Avoid Bleeding in High-Risk Patients Post-PCI – CRT Session

Mar 31, 2021 by
Matthew Litman, CRTonline.org

The TWILIGHT studies’ findings support the use of ticagrelor in selected high-risk patients as a bleeding-avoidance strategy after percutaneous coronary intervention. That was only one of the many takeaway messages from Saturday’s landmark session on antiplatelet therapy at CRT 2021 Virtual.

Shockwave IVL Use Expected to Continue Growing, CRT Discussants Say

Mar 31, 2021 by
Matthew Litman, CRTonline.org

Intravascular lithotripsy (IVL) is being used more often to treat severely calcified coronary lesions, and that can only be expected to continue to increase now that the Shockwave IVL device has been commercially approved in the U.S.

First-Time Myocardial Infarction Patients With Longer Working Hours at Greater Cardiovascular Risk

Mar 29, 2021 by
Natalie Morrison, CRTonline.org

Longer working hours among patients returning to work after a first myocardial infarction are associated with increased risk of coronary heart disease (CHD) events, according to a new prospective Canadian study.

Congenital Heart Disease COVID-19 Mortality Lines Up With General Population, But Worse Physiological Stage at Higher Risk

Mar 29, 2021 by
Natalie Morrison, CRTonline.org

COVID-19 mortality in patients with congenital heart disease (CHD) appears to be in line with the general population, despite concerns that these patients could have been at higher risk, according to a new international retrospective cohort study.

CRT Session: NIRS-IVUS Imaging Might Improve Identification of Vulnerable Plaques

Mar 28, 2021 by
Jason Wermers, CRTonline.org

Imaging coronary lesions with near-infrared spectroscopy (NIRS) and intravascular ultrasound (IVUS) can show which plaques are vulnerable to future cardiovascular events, which may inform how, or whether, these plaques should be treated in the future. That was a takeaway message from a focused session titled “Detection of a Vulnerable Plaque” held Saturday during Week 7 of CRT 2021 Virtual.

CRT Session: Physiology Could Bridge ‘Chasm’ Between ‘Blind’ and ‘Smart’ PCI

Mar 26, 2021 by
Matthew Litman, CRTonline.org

Justin E. Davies, MD, PhD, of Imperial College London, discussed the future of coronary physiology imaging, the DEFINE-GPS study, and their consequences for percutaneous coronary interventions (PCI), during his presentation Saturday at CRT Virtual 2021.

CRT Young Leaders Discuss Networking, Intellectual Property, Career Development

Mar 25, 2021 by
Jason Wermers, CRTonline.org

Nearly 50 Young Leaders attended the CRT 2021 Virtual Young Leader Symposium on Saturday.

Consortium Discusses Importance of Shock Networks, Treatment Strategies at CRT 2021 Virtual

Mar 25, 2021 by
Mohit Pahuja, CRTonline.org

The CRT 2021 Virtual meeting of the shock working group, the Cardiac Safety Research Consortium (CSRC), provided important insights on the work done by the group thus far.

Framingham Offspring Cohort Analysis: Each Additional Daily Serving of Ultra-Processed Foods Further Raises Cardiovascular Risk

Mar 22, 2021 by
Natalie Morrison, CRTonline.org

Each additional daily serving of ultra-processed foods is linked to a further rise in the associated risk of cardiovascular disease and death, according to a new analysis of the Framingham Offspring Cohort (FOS).

Swedish Registry: PDE5i Erectile Dysfunction Drugs Could Reduce Mortality Risk in Coronary Artery Disease Patients

Mar 22, 2021 by
Natalie Morrison, CRTonline.org

Phosphodiesterase 5 inhibitor (PDE5i) erectile dysfunction (ED) treatments such as Viagra (sildenafil) could lower mortality risk in men with stable coronary artery disease compared with alprostadil, researchers on a new Swedish registry study from the Karolinska Instituet claim.

PodCAST-PCI: Colchicine Given Pre-PCI Does Not Reduce No-Reflow Phenomenon in PCI Patients Versus Placebo

Mar 13, 2021 by
Natalie Morrison, CRTonline.org

Colchicine did not significantly reduce the rate of no-reflow phenomenon (NRP) or improve cardiovascular outcomes when administered immediately before primary percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI) according to follow-up over 1 year in the PodCAST-PCI trial.

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CRT Group Foundation is a not for profit corporation dedicated to providing educational services in the field of cardiology through the website, CRTonline.org and the Cardiovascular Research Technologies (CRT) annual symposium. CRT focuses on the advances and changes in the field of cardiovascular medicine. CRT is designed to provide access to the world’s leading clinicians and the latest research in order to improve practice and treatment outcomes for a variety of health care professionals.

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