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Drug-Eluting Stents in AMI: A Proven Strategy?
Use of Laser in Rescue AMI
Evolving Utility of Aspirin and Thienopyridines: New Insights Into Anti-Platelet Resistance
Low-Molecular Weight Heparins in ACS: New Insights from SYNERGY and STEEPLE
Why Dont Cardiologist Cool Patients



Novel Therapy on the Horizon for NSTEMI

A randomized phase 2 trial has provided promising results for losmapimod, an oral p38 MAPK inhibitor, in patients presenting with non ST-segment elevation MI. In addition to safety outcomes, the drug was associated with lower hsCRP and BNP concentrations.

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Low Risk Behavior Reduces MI Risk

A healthy lifestyle may be associated with reduced risk of cardiovascular disease. A study of 20,721 Swedish men has indicated that a combination of healthy diet, moderate alcohol consumption, no smoking, physical activity and absence of abdominal adiposity may reduce 4 of 5 MIs in men.

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REPRISE II Confirms Safety & Efficacy of Lotus

The REPRISE II study, designed to assess the safety and efficacy of the repositionable Lotus valve with a unique seal to minimize paravalvular leak, has shown successful implantation, retrieval, and repositioning in all participating patients. The rate for PPM requirement was 28.6%.

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The Epidemic of Diabetes Mellitus

A US population based study has indicated a doubling in the incidence and prevalence of DM between 1990-2008. Although a plateau was noted between 2008-2012, the incidence and prevalence of DM continues to rise in non-Hispanic black and Hispanic groups as well as those with a high school education or less.

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Untitled Document
PROTECT Trial: 5 Year Outcomes
- Edoardo Camenzind, MD
Reduction in office blood pressure after renal denervation in a large real world patient population with uncontrolled hypertension: interim 12-month results from the Global SYMPLICITY Registry
- Felix Mahfoud, MD
SYMPLICITY HTN-3 Trial: 12-month outcomes following un-blinding of subjects at 6 months
- George L. Bakris, MD
Aortic Valve-in-Valve: Insights from the Global Registry
- Danny Dvir, MD

Live Case Demonstration from Kusatsu Heart Center
Osamu Hatoh, MD
Treating CTO via Radial?
Richard R. Heuser, MD
Patient Selection for CTO Recanalization: What Are the Appropriate Criteria?
Tarek Helmy, MD
Treating CTOs: Is There Enough Evidence-Based Data or do We Need Further Randomized Clinical Trials?
Gerald S. Werner, MD, PhD
Indication for CTO PCI: Clinical Rationale and Appropriateness
J. Aaron Grantham, MD

 Click here to visit the WEBEX archives

Losmapimod, and a Novel p38 Mitogen-Activated Protein Kinase Inhibitor, in Non-ST-Segment Elevation Myocardial Infarction: A Randomized Phase 2 Trial.
L Newby, et al.
The Lancet 2014; 384:1187-1195
Low-Risk Diet and Lifestyle Habits in the Primary Prevention of Myocardial Infarction in Men: A Population-Based Prospective Cohort Study.
A Åkesson, et al.
JACC 2014; 64:1299-1306
Cardiovascular Function and Predictors of Exercise Capacity in Patients With Colorectal Cancer.
L Cramer, et al.
JACC 2014; 64:1310-1319
Incidence and Sequelae of Prosthesis-Patient Mismatch in Transcatheter Versus Surgical Valve Replacement in High-Risk Patients With Severe Aortic Stenosis: A PARTNER Trial Cohort-A Analysis.
P Pibarot, et al.
JACC 2014; 64:1323-1334
Transcatheter Aortic Valve Replacement for Severe Symptomatic Aortic Stenosis Using a Repositionable Valve System: 30-Day Primary Endpoint Results From the REPRISE II Study.
I Meredith, et al.
JACC 2014; 64:1339-1348
18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Enables the Detection of Recurrent Same-Site Deep Vein Thrombosis by Illuminating Recently Formed, Neutrophil-Rich Thrombus.
T Hara, et al.
Circ 2014; 130:1044-1052
Aspirin for the Prevention of Recurrent Venous Thromboembolism: The INSPIRE Collaboration.
J Simes, et al.
Circ 2014; 130:1062-1071
Fractional Flow Reserve–Guided PCI for Stable Coronary Artery Disease.
B De Bruyne, et al.
NEJM 2014; 371:1208-1217
Prevalence and Incidence Trends for Diagnosed Diabetes Among Adults Aged 20 to 79 Years, United States, 1980-2012.
L Geiss, et al.
JAMA 2014; 312:1218-1226
Impact of Diabetes Mellitus on Clinical Characteristics, Management, and In-hospital Outcomes in Patients With Acute Myocardial Infarction (from the NCDR).
T Rousan, et al.
AJC 2014; 114:1136-1144

Poll Archives
Shao-Liang Chen, MD, et al.
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Samir R. Kapadia, MD
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RIBS IV Clinical Trial
Fernando Alfonso MD, PhD
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Gregg W. Stone, MD
| Watch CardioTube Interview
Eric J. Dippel, MD
| Watch CardioTube Interview
Renal artery denervation with a new simultaneous multi-electrode catheter for treatment of resistant hypertension: 12-month update from the first-in-man study
Robert Whitbourn, MD, et al.
SYMPLICITY HTN-3: A Prospective, Randomized, Sham-Controlled Trial of Renal Sympathetic Denervation in Patients with Refractory Hypertension: Post Hoc Analyses of 12-Month Results
Deepak L. Bhatt, MD, MPH, et al.
SYMPLICITY HTN-3: Analysis of the African-American and Non-African American Populations
John M. Flack, MD, et al.
Preclinical Insights Into the Optimal Ablation Location for Renal Denervation Procedures
Robert J. Melder, ScD
Two-Year Clinical Results of OPTIMIZE Trial
Fausto Feres, MD, PhD
Cost-Effectiveness of Transcatheter Aortic Valve Replacement with a Self-Expanding Prosthesis Compared with Surgical Aortic Valve Replacement in High Risk Patients
Matthew R. Reynolds, MD
Multi-Vessel Versus Single-Vessel Treatment with Resolute Zotarolimus Eluting Stent in the RESOLUTE Global Clinical Program
Ganesh Manoharan, MD
Percutaneous Coronary Intervention of Small Vessels in the RESOLUTE Global Clinical Program: The Impact of Diabetes Mellitus
Milan Chag, MD
Percutaneous Coronary Intervention of Very Small Vessels in the RESOLUTE Global Clinical Program
Antonio Serra, MD
Patrick W. Serruys, MD
Randomized CTO-IVUS study
Yangsoo Jang, MD, PhD
ISAR-CLOSURE Randomized Trial
Stefanie Schupke , MD, et al.
P. Cervinka, MD, et al.
Axel Linke, MD , et al.
Two-Year Results From the CoreValve US Pivotal Trial
Steven J. Yakubov, MD
Katrin A. Fiedler, MD, et al.
SECURITY Randomized Clinical Trial
Antonio Colombo, MD
Yaling Han, MD
TRANSLATE-ACS Investigators
The IN.PACT Global Clinical Study
Gary M. Ansel, MD
1-year Results from the IN.PACT SFA II Trial
Adam C . Salisbury, MD, et al.
Serban Puricel, MD, et al.
I-LOVE-IT 2 Trial
Bo Xu, MD

Complex Patients Today and Tomorrow: Medtronic DES solutions from Resolute Integrity to bioresorbable stents
Prof. Sigmund Silber, MD
First Report on the Pivotal DESolve Nx trial: 6-month Clinical and Multimodality Imaging Results
Alexandre Abizaid, MD, PhD
One-Year Outcomes in 1010 Unselected Patients Treated with the PROMUS Element Everolimus-Eluting Stent: The Multicenter PROMUS Element European Post-Approval Surveillance Study
Raul Moreno, MD, et al.
Two-year clinical outcomes in the EVOLVE FHU trial
Ian Meredith, MD, PhD
Stephan Windecker, MD, et al.

Outcomes in More Than 7000 Patients With Diabetes After Implantation of the Resolute Zotarolimus-eluting Stent
Rosli Mohd Ali, MD
Safety update and long-term clinical outcomes from all studies in the RESOLUTE Global Clinical Program
Carlo Di Mario, MD
Final Five-year Outcomes from the Randomized Comparison of Zotarolimus-eluting Stents With Everolimus-eluting Stents in the RESOLUTE All Comers Trial
Stephan Windecker, MD
Angina Status & TLF Creep: Bioabsorbable Stents (BAS) & Drug-Eluting Stents (DES)
Medtronic, Inc.
Clinical outcomes associated with dual antiplatelet therapy interruption following implantation of the ResoluteTM zotarolimus-eluting stent
Stephan Windecker, MD
Four-year Outcomes from the Randomized Comparison of a Zotarolimus-eluting and an Everolimus-eluting Stent in the RESOLUTE All Comers Trial
Patrick W Serruys MD, PhD
Resolute in Bifurcation Lesions: Data from the RESOLUTE Clinical Program
Prof. Ran Kornowski, MD

Angiomyogenesis & Cell Therapy
Carotid Interventions

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