Recent developments of interest in cardiovascular medicine
About those controversial guidelines saying to keep eating red and processed meats ... the lead author has a history of questionable trade industry-sponsored studies. (Health Exec)
The EXCEL trial in left main disease "was a disgrace" with changes that biased the trial in favor of stents and their mortality disadvantage downplayed, charged cardiac surgeon David Taggart, MD, PhD, who said he withdrew his name from the New England Journal of Medicine 5-year data paper over such concerns. However, primary investigator Gregg Stone, MD, has repeatedly countered that no protocol change was made. (Twitter, TCTMD)
A proposed 72% cut to Medicare reimbursement of myocardial PET multiple perfusion services should be delayed, according to a letter to the Centers for Medicare and Medicaid Services from a group of members of Congress. (AuntMinnie.com)
For people who live alone, having a dog is linked to a longer life after a stroke or heart attack, a Swedish study found. (The Independent)
A smartphone app can quickly specify the cardiac implanted electrical device from a chest radiograph, which could be useful for emergency situations, according to a study in JACC: Clinical Electrophysiology. (Cardiovascular Business)
The FDA revised the rules for regulating digital health apps and artificial intelligence tools, saying it would take a risk-based approach that would let fitness trackers slide but take a sharper look at clinical decision tools, for example. (Advisory Board)
Idarucizumab (Praxbind) is as effective at reversing the activity of dabigatran (Pradaxa) in patients with as without renal impairment, found a pre-specified retrospective analysis of the RE-VERSE AD trial. (Journal of the American College of Cardiology)
The American College of Cardiology/American Heart Association guidelines may prevent more atherosclerotic cardiovascular disease events for a similar number needed to treat compared with guidelines from the U.S. Preventive Services Task Force and from the European Society of Cardiology. (JAMA Cardiology)
Nitrosamine contamination in sartans and ranitidine could come from five sources, as the European Medicines Agency detailed, ranging from contaminated raw or starting materials to formation during the processing of active pharmaceutical ingredients. (in-PharmaTechnologist.com)
Sleeping less than 6 hours a night was linked to all-cause mortality but not death from cardiovascular and cerebrovascular diseases, a study reported in Journal of the American Heart Association.
Chronic anticoagulation with dabigatran (Pradaxa) preserved cognition and reduced amyloid deposition in a mouse model of Alzheimer disease, researchers reported in the Journal of the American College of Cardiology.
The American Heart Association released a statement on interventional approaches to pulmonary embolism as a sort of review of the field and research needs but without hard clinical recommendations. (Circulation)
Atherosclerotic plaque contains lots of T-cells, with more that are CD4+ and active and differentiated among patients with a recent stroke, according to a single-cell level analysis in Nature Medicine.
Read the original article on Medpage Today: Industry Link in Disputed Meat Guideline; EXCEL Trial on Hotseat; PET Reimbursement