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Worse Patient Outcomes, Higher Costs in Waiting to Perform AVR in Patients With AS: Database Study

May 22, 2025 by
Bailey G. Salimes, CRTonline.org

PARIS – Aortic valve replacement (AVR) is best performed before symptom onset to improve outcomes in patients with aortic stenosis (AS) and reduce healthcare costs, a new study shows.

Coronary Function Testing Safe, Effective, Improves Quality of Life in ANOCA Patients: ILIAS-ANOCA Trial

May 22, 2025 by
Bailey G. Salimes, CRTonline.org

PARIS – Patients with angina and non-obstructive coronary arteries (ANOCA) can be safely and feasibly given routine ad-hoc coronary function testing (CFT) during invasive coronary angiography (ICA), according to results from the ILIAS ANOCA trial.

Combined Registry Study Finds PCBs vs SCBs Demonstrate Similar 2-Year Outcomes in Patients With CAD

May 22, 2025 by
Will Chu, CRTonline.org

Research comparing paclitaxel and sirolimus-coated balloons (PCB and SCB), used in coronary artery disease (CAD) treatment, finds similar outcomes between the two balloons with respect to MACE at 2-years follow-up.

EARLY TAVR Trial Shows Early TAVR Improves Cardiac Damage From Baseline at 2-Years Post-Procedure

May 22, 2025 by
Bailey G. Salimes, CRTonline.org

PARIS – Results from a 2-year follow-up analysis of the EARLY-TAVR trial show patients who have early transcatheter aortic valve replacement (TAVR) show improvement in cardiac damage compared with baseline, but patients in the clinical surveillance (no TAVR) group have worsening cardiac damage.

CMD Associated With Persistent Angina, Reduced Quality of Life in PCI Patients

May 22, 2025 by
Will Chu, CRTonline.org

An international study suggests that coronary microvascular dysfunction (CMD) is a major contributor to residual angina and reduced quality of life in patients who undergo successful percutaneous coronary intervention (PCI).

FFR and IVUS Show Similar Long-Term Outcomes in Coronary Stenosis Trial

May 22, 2025 by
Will Chu, CRTonline.org

Fractional flow reserve (FFR)-guided treatment and intravascular ultrasound (IVUS)-guided treatment for intermediate coronary stenosis result in similar long-term clinical outcomes, a new study shows.

Patients With Under-Expanded ACURATE neo2 Valve at Greater Risk of Death, Stroke, Rehospitalization: ACURATE IDE Post-Hoc Analysis

May 21, 2025 by
Bailey G. Salimes, CRTonline.org

PARIS – A post-hoc analysis of the ACURATE IDE trial shows that under-expansion of the ACURATE neo2 valve is associated with a higher risk for death, stroke or rehospitalization.

Pooled Cohort Study Shows Higher Device Success, Lower Safety Rates in Navitor vs Evolut and ACURATE valves

May 21, 2025 by
Bailey G. Salimes, CRTonline.org

PARIS – Higher device success but lower early safety rates are more prominent in the use of the Navitor (NAV) system in patients undergoing transcatheter aortic valve implantation (TAVI) compared with the use of the Evolut PRO/PRO+ (PRO) and ACURATE neo2 (NEO2) valves, a new pooled analysis shows.

De-escalation DAPT Protocol for ACS Management Halved Adverse Events vs Longer DAPT: Korean 4D-ACS Trial

May 21, 2025 by
Natalie Morrison, CRTonline.org

De-escalation protocols for dual antiplatelet therapies (DAPT) to manage acute coronary syndrome (ACS) during percutaneous coronary interventions (PCI) could enhance safety without compromising ischemic protection, the 4D-ACS trial concluded, after seeing a 49% reduction in adverse clinical events with shorter DAPT regimens.

FFR-Guided Angiography Improves Outcomes in Patients With CAD and Severe AS: FAITAVI Study

May 21, 2025 by
Bailey G. Salimes, CRTonline.org

PARIS – Patients with coronary artery disease (CAD) and severe aortic stenosis (AS) who undergo fractional flow reserve (FFR)-guided percutaneous coronary intervention (PCI) have fewer major adverse cardiac and cerbrovascular events (MACCE) at 12-months compared with those who undergo angiography-guided PCI, a new study shows.

Wide-Scale CEP Meta-Analysis Shows No Reduced Post-TAVI Overall Stroke Risk

May 21, 2025 by
Natalie Morrison, CRTonline.org

A new meta-analysis of more than 10,500 patients in the two largest randomized trials to-date testing the SENTINEL cerebral embolic protection (CEP) device as a way to protect against peri-procedural stroke during transcatheter aortic valve implantation (TAVI) confirmed there is no associated risk reduction overall for stroke.

Xcience DES, Absorb BVS Have Similar Outcomes in Final Results from COMPARE-ABSORB Trial

May 21, 2025 by
Bailey G. Salimes, CRTonline.org

PARIS – The bioresorbable vascular scaffold (BVS) Absorb and Xience drug-eluting stent (DES) show similar clinical outcomes at 7-year follow-up in the final results from the COMPARE-ABSORB trial.

Myval THV Still Non-Inferior to Sapien and Evolut at 1-Year in LANDMARK Study

May 21, 2025 by
Natalie Morrison, CRTonline.org

The Myval transcatheter heart valve (THV) was non inferior versus contemporary THVs in patients with symptomatic severe native aortic stenosis at 1-year post-procedure, according to the latest LANDMARK trial follow-up.

EMPOWER CAD Shows Promising 30-Day Results for Women With Calcified CAD

May 20, 2025 by
Bailey G. Salimes, CRTonline.org

PARIS – A 30-day analysis of the EMPOWER CAD trial demonstrates that the Shockwave coronary intravascular lithotripsy (IVL) device is effective in the treatment of women with coronary artery disease (CAD) and calcified lesions.

Lithotripsy for PCI of Severely Calcified Lesions Superior to Conventional Methods: BALI Study

May 20, 2025 by
Natalie Morrison, CRTonline.org

Using intravascular lithotripsy as a preparation for percutaneous coronary intervention (PCI) on severely calcified lesions reduces procedural and target vessel failures at 1 year without increasing risk, according to the international BALI trial — the first to support routine lithotripsy use for these patients.

Immediate Multivessel PCI Outshines Culprit-Only PCI in Patients With STEMI, Cardiogenic Shock: DanGer Shock Substudy

May 20, 2025 by
Bailey G. Salimes, CRTonline.org

PARIS – In patients with ST-segment myocardial infarction (STEMI) and left ventricular (LV)-failure cardiogenic shock, immediate multivessel percutaneous coronary intervention (PCI) is associated with reduced mortality at 6 months, a substudy of the DanGer shock trial shows.

Redo-TAVR More Feasible Choice for Bicuspid vs Tricuspid Aortic Valves: Simulation Study

May 13, 2025 by
Will Chu, CRTonline.org

Researchers reveal that patients with bicuspid aortic valves may have a higher chance of successful repeat transcatheter aortic valve replacement (redo-TAVR) compared to those with tricuspid valves.

Study Shows Ultrasound Imaging May Reduce Unnecessary Coronary Stenting in Patients Undergoing TAVR

May 13, 2025 by
Will Chu, CRTonline.org

New insights from a multicenter European study demonstrate that intravascular ultrasound (IVUS) can safely and effectively guide decisions to avoid unnecessary coronary stenting during transcatheter aortic valve replacement (TAVR).

Retrograde Approach Enhances CTO-PCI Success in Distal Cap Bifurcations, Study Finds

May 13, 2025 by
Will Chu, CRTonline.org

Japanese researchers suggest that complex cases of chronic total occlusion (CTO) with bifurcation at the distal cap can be treated successfully using refined strategies, especially with use of the retrograde approach.

Behavioral, Clinical Risk Factors Play a Role in Relationship Between CVD Deaths and Social Health Determinants

May 09, 2025 by
Bailey G. Salimes, CRTonline.org

The association between social determinants of health (SDOH) and increased rates of death due to cardiovascular disease (CVD) is mediated by behavioral and clinical risk factors, a new survey study shows.

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