Bioresorbable scaffolds (BRS) for percutaneous coronary intervention (PCI) have emerged with the promise to restore physiologic pulsatility and vasomotion, promote plaque regression and stabilization, and remove the trigger for late adverse events and stent thrombosis (ST). ST is a serious complication due to the high morbidity and mortality in both the short and long term. Although the rates have been reduced in newer-generation drug-eluting stents (DES) with advances in stent design and pharmacotherapy, the risk of ST continues to persist for all DES and was even higher with current-generation BRS. Causes associated with ST include incomplete neointimal formation, underexpansion, dissections, malapposition, hypersensitivity reactions, positive remodeling, and neoatherosclerosis. Intracoronary optical coherence tomography (OCT) visualizes in detail the majority of these features and has, therefore, become the gold standard to study their natural history and clinical importance. In this endeavour, the phenomenon coronary evaginationhas been observed by OCT in DES and is proposed to be an additional risk factor of late and very late ST.