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  • Editorial: Seeing clearly now: Imaging guidance modalities for left atrial appendage occlusion

    “I can see all obstacles in my way. Gone are the dark clouds that had me blind.” Johnny Nash's song about overcoming adversity speaks well to a central challenge in the field of left atrial appendage occlusion (LAAO): seeing clearly the structures and devices necessary to perform the procedure optimally. As procedural volumes increase, attention has shifted toward optimizing procedural efficiency, safety, and resource utilization. Central to this evolution is intraprocedural imaging.
    Contemporary multi-society guidelines emphasize that echocardiographic imaging rather than fluoroscopy alone can help minimize complications and ensure complete LAA seal [1]. Transesophageal echocardiography (TEE) combined with fluoroscopy has long been standard for guiding LAAO. This approach provides comprehensive visualization of LAA anatomy, reliable guidance for transseptal puncture, assessment of device sizing, and confirmation of adequate seal. However, TEE typically requires general anesthesia or deep sedation, necessitates a dedicated echocardiographer, and may cause esophageal discomfort or injury, especially in elderly patients. These limitations have prompted increasing interest in alternative, more minimalistic imaging approaches, especially transfemoral intracardiac echocardiography (TF-ICE).

    1. Transfemoral ICE

    TF-ICE is the second most frequently used LAA guidance modality, favored because TF-ICE provides LAAO-operator-driven imaging under conscious sedation and without general anesthesia in most cases [2]. Multiple studies have demonstrated comparable procedural success between TF-ICE- and TEE-guided LAAO, with a meta-analysis of 19 observational studies (n = 42,474; ICE n = 4415) reporting marginally higher procedural success with TF-ICE (odds ratio 1.33; 95% confidence interval 1.01–1.76; P = 0.04) and no difference in overall complication rates [3].

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