• Tissue-Selective Afib Ablation; ED Drug for HF? Pacemaker Warning

    Recent developments of interest in cardiovascular medicine

    Intensive blood pressure reduction may reduce the risk of hematoma expansion without improving outcomes in deep intracerebral hemorrhage, an exploratory trial analysis showed. (JAMA Neurology)

    Low-dose aspirin for people without symptomatic cardiovascular disease was associated with more intracranial hemorrhage, and more intracerebral hemorrhage in Asian and low-BMI patients. (JAMA Neurology)

    Google is getting into gene editing for heart disease with its Verve Therapeutics start-up helmed by heavy hitter Sekar Kathiresan, MD.

    In news from the Heart Rhythm Society meeting in San Francisco:

    • Rotor ablation flopped when added to conventional pulmonary vein isolation for atrial fibrillation in the REAFFIRM trial. (Mass Device)
    • Novel pulsed field ablation technology isolated the pulmonary vein durably but "with a degree of tissue selectivity and a safety profile heretofore not described for cardiac ablation." (ACC.org)
    • The Emblem subcutaneous ICD for primary prevention in low ejection fraction patients had a 95.8% rate of freedom from complications, a 99.6% rate of successful implantation at 30 days, and a 99.2% rate of successful defibrillator conversion. (Mass Device)
    • Amid low rates of referral to electrophysiologists and low implantation ratesfor cardiac resynchronization therapy defibrillators (CRT-D) and ICDs in eligible patients, women and minorities got even fewer. (BioSpace

    Erectile dysfunction drug tadalafil (Cialis) appeared to reverse heart failure by boosting heart contraction strength -- in sheep. (Scientific Reports)

    Certain Medtronic pacemakers and cardiac resynchronization therapy pacemakers got a safety alert from the FDA due to risk of complete premature battery depletion from a crack in the capacitor that has led to three reported events and one death.

    A (former) Kentucky cardiologist was sentenced to 5 years in prison for unnecessary diagnostic catheterization and stenting. (Cardiovascular Business).

    pulsating infrarenal aortic aneurysm over 4 inches in diameter was reported in Belgium. (New England Journal of Medicine)

    Researchers developed a risk score for fracture in the year after an ischemic stroke. (JAMA Neurology)

    Electronic medical record alerts of medication combinations that could prolong the QT interval are being instituted by the University of Arizona. (KVOA.com)

    The FDA cleared the RhythmAnalytics wearable ECG device for detecting 15 different types of arrhythmia including ventricular arrhythmias and ectopic beats and atrial fibrillation. (FDA News)

    Cloud-based app and analytic software eMurmur ID also gained clearance as part of an automated heart murmur detection with a third-party digital stethoscope. (MobiHealthNews)

    BioCardia announced its Avance steerable introducers were cleared for use with various cardiovascular catheters, including interatrial septum access. (Globe Newswire)

    The agency approved the Vici Venous Stent for iliofemoral venous obstructive disease. (WBJournal.com)

    Source:

    Read the original article on Medpage Today: Tissue-Selective Afib Ablation; ED Drug for HF? Pacemaker Warning

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