• Fourth Sartan Carcinogen; Vacation MI; N=1 Trials

    Recent developments of interest in cardiovascular medicine

    fourth type of carcinogen -- the solvent N,N-Dimethylformamide -- has been reported in valsartan (the third type was reported in March). While within the FDA's "safe" threshold, the citizen's petition by online pharmacy Valisure called for action because that limit is way out of line with other sartan contaminants. (Cardiovascular Businessin-PharmaTechnologist)

    About one-third of young athletes screened for heart health before sports participation had high blood pressure. (Heart)

    Weight gain is tied to higher atrial fibrillation incidence, but non-surgical weight loss may not have the opposite effect, a meta-analysis found. (Heart)

    Vacation-induced heart attack? It's a thing, Inside Edition writes.

    Stalled out progress in heart disease and stroke gets some attention from the Wall Street Journal.

    Alexa and other smart speakers could be used to detect a heart attack during sleep, according to a proof-of-concept study. (Cardiovascular Business)

    "I call upon our heart failure community to formalize the thousands of single-patient trials that we conduct in clinical practice everyday," Christopher O'Connor, MD, editor-in-chief of JACC: Heart Failure, wrote in its editor's page.

    It's a Class I recall for Cook's Advance Enforcer 35 Focal Force percutaneous transluminal angioplasty balloon catheter, which can burst below the rated burst pressure, the FDA announced.

    Bursting risk also prompted a field safety notice for Edwards Lifesciences' IntraCludeballoon for cardiopulmonary bypass. (Mass Device)

    Artificial intelligence-based algorithm HealthICH gained FDA clearance for detecting intracranial hemorrhages on standard head CT scans. (Radiology Business)

    Mutations in the TTN gene are often found in dilated cardiomyopathy, but a study showed most carriers never develop the disease, so genetic testing in healthy people probably isn't a good idea. (Circulation)

    Cut out aspirin and avoid the combination of a vitamin K antagonist plus dual antiplatelet therapy for atrial fibrillation patients who have coronary artery disease, a meta-analysis concluded in JAMA Cardiology.

    Atrial fibrillation is linked to dementia even in the absence of stroke, but oral anticoagulation might help, researchers reported in the European Heart Journal.

    Source:

    Read the original article on Medpage Today: Fourth Sartan Carcinogen; Vacation MI; N=1 Trials

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