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  • Drug-Eluting Versus Bare-Metal Stents in Older Patients: A Meta-Analysis of Randomized Controlled Trials

    Highlights

    • Drug-eluting stents (DES) were associated with low major adverse cardiovascular events (MACE).
    • Major bleeding events were similar between DES and bare-metal stents.
    • Short dual-antiplatelet therapy (≤6 months) with DES was associated with low MACE.
    • High bleeding rates were evident with longer dual-antiplatelet therapy duration.

    Abstract

    Background

    Despite the high prevalence of ischemic heart disease in older patients, there is a substantial lack of evidence to guide clinical decision-making in this population. Hence, we performed a meta-analysis to determine the safety and efficacy of percutaneous coronary intervention (PCI) with drug-eluting stents (DES) versus bare-metal stents (BMS).

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